ABSTRACT
El síndrome de Goodpasture es más frecuente en varones, adultos jóvenes. Se presento una paciente de sexo femenino de doce años de edad con historia de palidez, astenia y adinamia, expectoración hemoptoica y dificultad respiratoria rápidamente progresiva, anemia microcítico y falla renal aguda que evolucionó con insuficiencia respiratoria grave e irreversible secundario a hemorragia pulmonar masiva. Los exámenes anatomopatológicos mostraron hemosiderosis pulmonar y glomerulonefritis crecéntica, compatibles con síndrome de Goodpasture
Subject(s)
Humans , Female , Anti-Glomerular Basement Membrane Disease/diagnosis , Anti-Bacterial Agents/therapeutic use , Cause of Death , Diagnosis, Differential , Glomerulonephritis , Hemosiderosis , Iron/therapeutic use , Anti-Glomerular Basement Membrane Disease/physiopathology , Anti-Glomerular Basement Membrane Disease/drug therapyABSTRACT
We report a 26 years old male with secondary amyloidosis and chronic renal failure who consulted due to rapidly growing goiter associated with coarseness and dysphagia. Serum levels of thyroid hormones and TSH were normal and a neck CT scan showed a big mass in the anterior lateral regions, thet compressed neighboring structures. The patient was subjected to a total thyroidectomy and the pathological study revealed a diffuse fatty and amyloid infiltration of the thyroid gland. There was no evidence of malignancy